Oklahoman here! I’ve personally haven’t spent much time in this part of the state. It’s was historically referred to as “No Man’s Land” if that gives you any idea. The panhandle has a much more arid, high plains type climate than other parts of the state. I believe there are literal sand dunes out that way. Oklahoma’s highest point, Black Mesa, is in the panhandle. Im told Black Mesa is a great camping spot for star-gazing, but I’ve never been. As far as I’m aware it’s mostly right-wing but jobs living in that area. I seem to recall a few local news stories about people in that part of the state making a big stink about trans kids trying to use the bathroom and so forth.
Check out the 1994 “The Stand” miniseries or read the book by Stephen King. It explores the idea of the main bad guys and their leader, who is essentially the devil, taking up residence in Las Vegas.